Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

Method Comparison

The comparison table contains the following columns:

  • Trendable?: Indicates whether both methods use the same component code and results are trendable in Epic.
  • Bias: The average absolute difference between Roche and Beckman results. A positive value means Roche results are higher on average.
  • Percent Bias: Blue shading and bars extending left indicate negative bias (Beckman higher on average); orange shading and bars extending right indicate positive bias (Roche higher on average). Longer bars indicate greater magnitude.
  • Slope: The slope of the linear regression of Roche onto Beckman, representing proportional bias between the methods. “Not comparable” indicates that the methods were too poorly correlated for direct patient-result comparison.
  • R2 (Coefficient of Determination): How closely the regression fits the paired results.

These data can help when comparing results across platforms, but should not be used to convert a result directly from one method to the other.

Test Name Beckman Roche Trendable? Bias Percent Bias Slope Coefficient of Determination (R2)
Apolipoprotein B APOB APOB -3.27 mg/dL -3.71% 0.911 0.9879
Cholesterol (HDL) HDL HDLRD 3.11 mg/dL 5.58% 1.004 0.812
Cholesterol (Total) CHOL CHOL -5.2 mg/dL -2.80% 1.032 0.9559
Cholesterol/HDL Ratio CHRAT CHRTRD Not comparable
Direct Low Density Lipoprotein DLDL DLDL 23.7 mg/dL 20.14% 1.418 0.9691
LDL Cholesterol, Calculated LDLN LDLNRD Not comparable
Non HDL Cholesterol NONHDL NHDLRD Not comparable
Triglycerides TRIG TRIG -20.72 mg/dL -8.29% 0.959 0.9502

Reference Ranges

Name
Beckman
Roche
Apolipoprotein B
Name: Apolipoprotein B
Mnemonic: APOB
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 0-130 0- 0-130
Effective date: 09/14/2026
Name: Apolipoprotein B
Mnemonic: APOB
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 0-130 0- 0-130
Effective date: 09/14/2026
Cholesterol (HDL)
Name: HDL Cholesterol
Mnemonic: HDL
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- >49 0- >39
Effective date: 09/14/2026
Name: Cholesterol (HDL) (Roche)
Mnemonic: HDLRD
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- >49 0- >39
Effective date: 12/17/2025
Cholesterol (Total)
Name: Cholesterol (Total)
Mnemonic: CHOL
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- <210 0- <210
Effective date: 09/14/2026
Name: Cholesterol (Total)
Mnemonic: CHOL
Units: mg/dL
Method Code: FMPRO1
Female Male
AgeRange AgeRange
0- <210 0- <210
Effective date: 03/12/2026
Cholesterol/HDL Ratio
Name: Cholesterol/HDL Ratio
Mnemonic: CHRAT
Units: not defined
Method Code: default Effective date: 03/09/2010
Name: Cholesterol/HDL Ratio (Roche)
Mnemonic: CHRTRD
Units: not defined
Method Code: default
Direct Low Density Lipoprotein
Name: Direct Low Density Lipoprotein
Mnemonic: DLDL
Units: mg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- <160 0- <160
Effective date: 09/14/2026
Name: Direct Low Density Lipoprotein
Mnemonic: DLDL
LDL Cholesterol, Calculated
Name: LDL Cholesterol, Calculated
Mnemonic: LDLN
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- <160 0- <160
Effective date: 03/02/2026
Name: LDL Cholesterol, Calculated (Roche)
Mnemonic: LDLNRD
Units: mg/dL
Method Code: default
Non HDL Cholesterol
Name: Non HDL Cholesterol
Mnemonic: NONHDL
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- <190 0- <190
Effective date: 03/02/2026
Name: Non HDL Cholesterol (Roche)
Mnemonic: NHDLRD
Units: mg/dL
Method Code: default
Triglycerides
Name: Triglycerides
Mnemonic: TRIG
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- <175 0- <175
Effective date: 09/14/2026
Name: Triglycerides
Mnemonic: TRIG
Units: mg/dL
Method Code: FMPRO1
Female Male
AgeRange AgeRange
0- <175 0- <175
Effective date: 03/12/2026