Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

All BMP Liver Kidney Lipids Endocrine Tumor Marker Cardiac Misc Drugs Heme

Method Comparison

The comparison table contains the following columns:

  • Trendable?: Indicates whether both methods use the same component code and results are trendable in Epic.
  • Bias: The average absolute difference between Roche and Beckman results. A positive value means Roche results are higher on average.
  • Percent Bias: Blue shading and bars extending left indicate negative bias (Beckman higher on average); orange shading and bars extending right indicate positive bias (Roche higher on average). Longer bars indicate greater magnitude.
  • Slope: The slope of the linear regression of Roche onto Beckman, representing proportional bias between the methods. “Not comparable” indicates that the methods were too poorly correlated for direct patient-result comparison.
  • R2 (Coefficient of Determination): How closely the regression fits the paired results.

These data can help when comparing results across platforms, but should not be used to convert a result directly from one method to the other.

Test Name Beckman Roche Trendable? Bias Percent Bias Slope Coefficient of Determination (R2)
C Reactive Protein HSCRP HCRPRD ❌ -1.7744 mg/L -17.90% 0.853 0.9706
Creatine Kinase Total Activity CK CK ✅ 44.57 U/L 15.58% 1.134 0.9923
Homocysteine HMCY HMCY ✅ -1.487 mcmol/L -10.62% 0.932 0.8034
NT-ProBNP BNAP NTBPRD ❌ Not comparable
Troponin T TROPBC TROPRD ❌ Not comparable

Reference Ranges

Name
Beckman
Roche
C Reactive Protein
Name: C Reactive Protein (Beckman)
Mnemonic: HSCRP
Units: mg/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0.0-10.0 0- 0.0-10.0
Effective date: 09/24/2018
Name: C Reactive Protein (Roche)
Mnemonic: HCRPRD
Units: mg/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0.0-9.9 0- 0.0-9.9
Effective date: 04/19/2026
Creatine Kinase Total Activity
Name: Creatine Kinase Total Activity
Mnemonic: CK
Units: U/L (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 26-192 0- 39-308
Effective date: 09/14/2026
Name: Creatine Kinase Total Activity
Mnemonic: CK
Homocysteine
Name: Homocysteine
Mnemonic: HMCY
Units: mcmol/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-16 0- 0-16
Effective date: 09/14/2026
Name: Homocysteine
Mnemonic: HMCY
Units: mcmol/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-16 0- 0-16
Effective date: 09/14/2026
NT-ProBNP
Name: B-Type Natriuertic Peptide
Mnemonic: BNAP
Units: pg/mL
Method Code: default
Female Male
AgeRange AgeRange
0- <101 0- <101
Effective date: 09/19/2006
Name: NT-ProBNP
Mnemonic: NTBPRD
Units: pg/mL
Method Code: default
Female Male
AgeRange AgeRange
0-49y 0-450 0-49y 0-450
50y-74y 0-900 50y-74y 0-900
75y- 0-1800 75y- 0-1800
Effective date: 09/02/2026
Troponin T
Name: Troponin I (Beckman)
Mnemonic: TROPBC
Units: ng/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-15 0- 0-20
Effective date: 04/01/2026
Name: Troponin T (Roche)
Mnemonic: TROPRD
Units: ng/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-14 0- 0-22
Effective date: 04/01/2026