Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

Method Comparison

The comparison table contains the following columns:

  • Trendable?: Indicates whether both methods use the same component code and results are trendable in Epic.
  • Bias: The average absolute difference between Roche and Beckman results. A positive value means Roche results are higher on average.
  • Percent Bias: Blue shading and bars extending left indicate negative bias (Beckman higher on average); orange shading and bars extending right indicate positive bias (Roche higher on average). Longer bars indicate greater magnitude.
  • Slope: The slope of the linear regression of Roche onto Beckman, representing proportional bias between the methods. “Not comparable” indicates that the methods were too poorly correlated for direct patient-result comparison.
  • R2 (Coefficient of Determination): How closely the regression fits the paired results.

These data can help when comparing results across platforms, but should not be used to convert a result directly from one method to the other.

Test Name Beckman Roche Trendable? Bias Percent Bias Slope Coefficient of Determination (R2)
Ferritin FER FERRD 90.78 ng/mL 45.31% 1.436 0.9885
Folate, SRM FOLAT FOLAT -0.875 ng/mL -8.28% 1.043 0.8358
Haptoglobin Quant HPT HPT -4.23 mg/dL -2.63% 1 0.9785
Iron, SRM FE FE -0.43 mcg/dL -0.46% 0.942 0.9936
Transferrin TRSF TRSFRD -8.4 mg/dL -3.85% 1.023 0.9917
Vitamin B12 (Cobalamin) VITB12 VITB12 299.9 pg/mL 53.40% 1.509 0.996

Reference Ranges

Name
Beckman
Roche
Ferritin
Name: Ferritin (Beckman)
Mnemonic: FER
Units: ng/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 10-180 0- 20-230
Effective date: 05/01/2009
Name: Ferritin (Roche)
Mnemonic: FERRD
Units: ng/mL
Method Code: default
Female Male
AgeRange AgeRange
0- 13-150 0- 30-400
Effective date: 09/13/2026
Folate, SRM
Name: Folate, SRM
Mnemonic: FOLAT
Units: ng/mL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- >4.6 0- >4.6
Effective date: 09/14/2026
Name: Folate, SRM
Mnemonic: FOLAT
Haptoglobin Quant
Name: Haptoglobin Quant
Mnemonic: HPT
Units: mg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 30-200 0- 30-200
Effective date: 09/14/2026
Name: Haptoglobin Quant
Mnemonic: HPT
Iron, SRM
Name: Iron, SRM
Mnemonic: FE
Units: mcg/dL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 35-145 0- 50-150
Effective date: 09/14/2026
Name: Iron, SRM
Mnemonic: FE
Transferrin
Name: Transferrin (Beckman)
Mnemonic: TRSF
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 192-382 0- 180-329
Effective date: 03/01/2015
Name: Transferrin (Roche)
Mnemonic: TRSFRD
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 200-360 0- 200-360
Effective date: 09/02/2026
Vitamin B12 (Cobalamin)
Name: Vitamin B12 (Cobalamin)
Mnemonic: VITB12
Units: pg/mL (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 232-1245 0- 232-1245
Effective date: 09/14/2026
Name: Vitamin B12 (Cobalamin)
Mnemonic: VITB12