Prenatal Quad Screen, 2nd Trimester (Sendout)

General Information

Lab Name
Prenatal Quad Screen, 2nd Trimester (Sendout)
Lab Code
RPQUAD
Epic Name
Prenatal Quad Screen, 2nd Trimester (Sendout)
External Test Id
3000143
Description

Ordering Recommendation: Second-trimester screening test for fetal risk of trisomy 21 (Down syndrome), trisomy 18 (Edwards), and open neural tube defects (ONTD, spina bifida).

Patient Preparation: Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. The recommended time for maternal serum screening is 16 to 18 weeks gestation.

Ordering Requirements:

References
Synonyms
2nd Trimester Screening, 3000143, AFP 4 Marker, AFP 4 Marker Screen, AFP MS4 (Quad), Alpha Fetoprotein, Estriol, hCG, Inhibin, Maternal Screening, QUAD, Quad AFP, Quad Screening, RMQUAD, trisomy
Components

Interpretation

Method

Quantitative Chemiluminescent Immunoassay

Reference Range
See individual components
Ref. Range Notes

Refer to report.

Ordering & Collection

Specimen Type
Blood
Collection

9 mL blood in GOLD SST or RED TOP tube

Forms & Requisitions
Handling Instructions

Outside Laboratories:

  • Centrifuge sample and transfer 3 mL (1 mL min) serum to a separate plastic vial. Serum must be separated from cells within 2 hours of collection. Refrigerate serum.
  • Submit a completed ARUP Maternal Serum Testing Patient History Form along with the DLMP requisition.* Failure to provide the mandatory information may result in test delays.
    • *Use client-specific requisition when available. To obtain a client-specific requisition, contact Client Support Services via email at: commserv@uw.edu.

Stability (after separation from cells): Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 72 hours.

Unacceptable Conditions: Plasma, hemolyzed specimens.

Quantity
Requested: 3 mL serum
Minimum: 1 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer 3 mL (1 mL minimum) serum to a separate plastic vial. Serum must be separated from cells within 2 hours of collection. Refrigerate serum.

Sendouts:

  • Order ARUP Test: 3000143.
  • Interfaced: Yes. [Interface: 602; Department: ARPR]
  • For orders placed in Epic: The answers to the order questions will file from Epic to ARUP via the interface.
  • For outside orders not placed in Epic: A completed ARUP Patient History Form is required. If not provided, send an HC1 Task to CSS asking them to follow up with the client to obtain the form.

Stability (after separation from cells): Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 72 hours.

Unacceptable Conditions: Plasma, hemolyzed specimens.

Misc Sendout

Performance

Lab Department
Sendouts ARUP Lab (RF)(ARPR)
Frequency
Performed: Sunday - Saturday. Reported: 2-3 days from sample receipt at ARUP. Missing information may further delay testing.
Available STAT?
No
Performing Location(s)
Sendout ARUP Laboratories, Inc.
800-522-2787

500 Chipeta Way
Salt Lake City, UT 84108

Billing & Coding

CPT Codes
81511
LOINC
48800-7
Interfaced Order Code
UOW5129