Fungal Antibody Panel, CSF (Sendout)

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General Information

Lab Name
Fungal Antibody Panel, CSF (Sendout)
Lab Code
RCFAP
Epic Name
Fungal Antibody Panel, CSF (Sendout)
External Test Id
3000230
Description

Ordering Recommendation: This test detects antibodies to Aspergillus, Coccidioides, and Histoplasma by complement fixation and Blastomyces by immunoassay. Not recommended as a standalone test for the diagnosis of fungal infection of the central nervous system. Pathogen-specific tests are preferred. For Coccidioides only, refer to test Coccidioides Antibodies, CSF (Sendout) [RCCOCC].

    Test Algorithm: If Blastomyces antibodies are equivocal or positive by immunoassay, then Blastomyces Antibody by ID, CSF [RCBLID] will be added at additional charge.

    References
    1. ARUP Laboratories Fungal Antibodies with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF
    Synonyms
    3000230, ASP, Aspergillus, Blasto, Blastomyces, CF, Cocci, Coccidioides, Complement Fixation, Fungal Antibody, Fungal Serology, Histo, Histoplasma
    Components
    Code Name
    RCCOC Coccidioides Antibody by CF, CSF
    RCHISM Histoplasma Mycelia Antibody by CF, CSF
    RCHISY Histoplasma Yeast Antibody by CF, CSF
    RCASP Aspergillus Antibody by CF, CSF
    RCBLM Blastomyces Antibody by EIA, CSF

    Interpretation

    Guidelines
    Method

    Coccidioides, Histoplasma M, Histoplasma Y, Aspergillus Abs: Semi-Quantitative Complement Fixation

    Blastomyces Ab: Semi-Quantitative Enzyme-Linked Immunosorbent Assay

    Reflex Blastomyces Ab: Immunodiffusion

    Reference Range
    See individual components
    Ref. Range Notes

    Reference Interval:

    Coccidioides Ab by CF, CSF <1:2
    Aspergillus Antibody, CSF (CF) <1:2
    Histoplasma M, CSF (CF) <1:2
    Histoplasma Y, CSF (CF) <1:2
    Blastomyces Antibodies EIA, CSF <=0.9 IV
    References
    1. ARUP Laboratories Fungal Antibodies with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF

    Ordering & Collection

    Specimen Type
    CSF
    Collection

    Collect 1 mL cerebrospinal fluid (CSF)

    Handling Instructions

    Outside Laboratories: Refrigerate CSF.

    Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 48 hours.

    Unacceptable Conditions: Submission of body fluids other than CSF. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.

    Quantity
    Requested: 1 mL CSF
    Minimum: 0.6 mL CSF

    Processing

    Receiving Instructions

    Refrigerate CSF.

    Sendouts:

    • Order ARUP Test: 3000230.
    • Interfaced: Yes [Interface 602; Department ARPR]

    Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hrs.

    Unacceptable Conditions: Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens. Avoid repeated freeze/thaw cycles.

    Misc Sendout

    Performance

    Lab Department
    Sendouts ARUP Lab (RF)(ARPR)
    Frequency
    Performed: Sunday through Saturday. Reported: 2-6 days from sample receipt at ARUP Laboratories.
    Available STAT?
    No
    Performing Location(s)
    Sendout ARUP Laboratories, Inc.
    800-522-2787

    500 Chipeta Way
    Salt Lake City, UT 84108

    Billing & Coding

    CPT Codes
    86606, 86612, 86635, 86698x2
    LOINC
    56146-4