Fungal Antibody Panel, CSF (Sendout)

General Information

Lab Name

Lab Code

RCFAP

Epic Ordering

Fungal Antibody Panel, CSF (Sendout)

External Test Id

3000230

Description

Ordering Recommendation: This test detects antibodies to Aspergillus, Coccidioides, and Histoplasma by complement fixation and Blastomyces by immunoassay. Not recommended for the diagnosis of fungal infection of the central nervous system. For Coccidioides only, refer to test Coccidioides Antibodies, CSF (Sendout) [RCCOCC].

Test Algorithm: If Blastomyces antibodies are equivocal or positive by immunoassay, then Blastomyces Antibody by ID, CSF [RCBLID] will be added at additional charge.

References

ARUP Laboratories Fungal Antibodies with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF

Synonyms

3000230, ASP, Aspergillus, Blasto, Blastomyces, CF, Cocci, Coccidioides, Complement Fixation, Fungal Antibody, Fungal Serology, Histo, Histoplasma

Components

Code	Name
RCCOC	Coccidioides Antibody by CF, CSF
RCHISM	Histoplasma Mycelia Antibody by CF, CSF
RCHISY	Histoplasma Yeast Antibody by CF, CSF
RCASP	Aspergillus Antibody by CF, CSF
RCBLM	Blastomyces Antibody by EIA, CSF

Interpretation

Method

Coccidioides, Histoplasma M, Histoplasma Y, Aspergillus Abs: Semi-Quantitative Complement Fixation

Blastomyces Ab: Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reflex Blastomyces Ab: Immunodiffusion

Reference Range

See individual components

Ref. Range Notes

Reference Interval:

Coccidioides Ab by CF, CSF	<1:2
Aspergillus Antibody, CSF (CF)	<1:2
Histoplasma M, CSF (CF)	<1:2
Histoplasma Y, CSF (CF)	<1:2
Blastomyces Antibodies EIA, CSF	<=0.9 IV

Guidelines

Washington DOH Notifiable Conditions

Ordering & Collection

Specimen Type: CSF
Collection: Collect 1 mL cerebrospinal fluid (CSF)
Handling Instructions: Outside Laboratories: Refrigerate CSF.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles); Ambient: 48 hours.

Unacceptable Conditions: Submission of body fluids other than CSF. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.
Quantity: requested: 1 mL CSF
minimum: 0.6 mL CSF

Processing

Processing

Refrigerate CSF.

Sendouts:

Order ARUP Test: 3000230.
Interfaced: Yes [Interface 602; Department ARPR]

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hrs.

Unacceptable Conditions: Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens. Avoid repeated freeze/thaw cycles.

Performance

LIS Dept Code

Sendouts ARUP Lab (RF) (ARPR)

Performing Location(s)

Sendout	ARUP Laboratories, Inc. 800-522-2787 500 Chipeta Way Salt Lake City, UT 84108

Frequency

Performed: Sunday through Saturday. Reported: 2-6 days from sample receipt at ARUP Laboratories.

Available STAT?

Billing & Coding

CPT codes: 86606, 86612, 86635, 86698x2
LOINC: 56146-4