Syphilis Reflexive Screen

General Information

Lab Name
Syphilis Reflexive Screen
Lab Code
SYPHRE
Epic Name
Syphilis Reflexive Screen
Description

This test is performed in-house at UW. If the screening treponemal antibody result is positive, reflexive non-treponemal (RPR) testing (RPR Screen with Reflex to Titer [RPRQUW]) will be automatically performed. To diagnose congenital syphilis in neonate/infants and to monitor treatment responses, quantitative RPR testing (RPR Screen with Reflex to Titer [RPRQUW] or RPR Titer, Quantitative [RPRQT]) should be performed instead of the serologic syphilis screen. For congenital syphilis diagnosis, concurrent quantitative RPR testing of maternal serum should be obtained, to enable comparison between neonatal and maternal RPR titers.

Synonyms
reagin, RPR, Treponema pallidum
Components

Interpretation

Method

Multiplex Immunoassay

Reference Range
See individual components

Ordering & Collection

Specimen Type
Serum
Collection

6mL Blood in GOLD SST tube.

Acceptable Specimen: RED Top tube

Unacceptable Specimen: Green, Lavender, Orange RST or Blue Top tube.

Note: Plasma can only be used if a serum sample is not available and the use of plasma has been approved by the Lab Medicine Resident. If screening results are not negative, a serum sample will need to be drawn for in-house RPR and mandatory State Lab supplemental testing, leading to reporting delays.

Handling Instructions

Stability: Refrigerated: 14 days (preferred); Frozen at -20°C or colder: Long Term (avoid repeated freeze-thaws)

Quantity
Requested: 2.5 mL
Minimum: 2 mL

Processing

Receiving Instructions

Refrigerate serum.
STAT requests need approval from Lab Medicine Resident on call.

Misc Sendout

Performance

Lab Department
Immunology(IMM)
Frequency
Monday through Friday
Available STAT?
No
Performing Location(s)
UW-MT Immunology
206-520-4600

Clinical Lab, Room NW220,
University of Washington Medical Center,
1959 NE Pacific street, Seattle, WA 98195

Billing & Coding

CPT Codes
86780
LOINC
47236-5
Interfaced Order Code
UOW6133