Trypanosoma cruzi IgG Antibody (Sendout)

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General Information

Lab Name
Trypanosoma cruzi IgG Antibody (Sendout)
Lab Code
RTRYPG
Epic Name
Trypanosoma cruzi IgG Antibody (Sendout)

Order using Lab Undefined Order [LABUND]
External Test Id
0051076
Description

Useful For: Aiding in the diagnosis of non-acute (chronic phase) Chagas disease (T. cruzi).

    Ordering Requirements: Orders must be approved by the Laboratory Medicine Resident (LMR) or Microbiology fellow on-call.

      Ordering Guidance: The preferred first-line test is Trypanosoma cruzi Antibody Panel (Sendout) [RCRUZI]. If results from the Mayo panel are discordant, this test to ARUP may be used as a tie-breaker, although it is less sensitive than other options. Consider alternative testing available at Eurofins Viracor, with guidance from the LMR or Micro fellow.

      Synonyms
      0051076, American trypanosomiasis, Chagas Antibody IgG, Chagas Disease, T. cruzi, Tcruzi IgG Ab, Trypanosomiasis
      Components
      Code Name
      RTRYPR Trypanosoma cruzi IgG Antibody

      Interpretation

      Guidelines
      Method

      Semi-Quantitative Enzyme-Linked Immunosorbent Assay

      Reference Range
      See individual components
      Ref. Range Notes
      Reference Interval: <=1.0 IV

      Interpretation:

      <=1.0 IV:

      Negative - No significant level of Trypanosoma cruzi IgG antibody detected.
      1.1 IV:

      Equivocal - Questionable presence of Trypanosoma cruzi IgG antibody detected. Repeat testing in 10-14 days may be helpful.
      >=1.2 IV: Positive - IgG antibodies to Trypanosoma cruzi detected, which may suggest current or past infection.
      Interferences and Limitations

      Cautions: This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps). According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific.

      Ordering & Collection

      Specimen Type
      Blood
      Collection

      3 mL blood in GOLD TOP SST or RED TOP tube

      Approval Required
      Laboratory Medicine Resident (LMR) or Microbiology Fellow approval is required.
      Handling Instructions

      Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

      Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.

      Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

      Quantity
      Requested: 0.5 mL serum
      Minimum: 0.3 mL serum

      Processing

      Receiving Instructions

      Centrifuge sample and transfer serum to a separate plastic vial within two hours of collection. Refrigerate serum.

      Sendouts:

      • Order ARUP Test: 0051076.
      • Interfaced: Yes. [Interface Number: 602; Department: ARPR]

      Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.

      Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

      Misc Sendout

      Performance

      Lab Department
      Sendouts ARUP Lab (RF)(ARPR)
      Frequency
      Performed: Wednesday. Reported: 1-8 days.
      Available STAT?
      No
      Performing Location(s)
      Sendout ARUP Laboratories, Inc.
      800-522-2787

      500 Chipeta Way
      Salt Lake City, UT 84108

      Billing & Coding

      CPT Codes
      86753
      LOINC
      59387-1