Factor XIII Qualitative (Sendout)
General Information
- Lab Name
- Factor XIII Qualitative, Rflx 1:1 Mix (Sendout)
- Lab Code
- RF13
- Epic Ordering
- Factor XIII Qualitative, Rflx 1:1 Mix (Sendout)
- External Test Id
- 3016927
- Description
Ordering Recommendation: Most useful if a severe FXIII deficiency is suspected (<1% of normal activity). Distinguishes between FXIII deficiency and a FXIII inhibitor. Abnormal results should be confirmed with quantitative testing. Severe deficiency may be inherited or acquired (typically due to a factor XIII antibody).
Test Algorithm: If Factor 13 Qualitative has a result of "Lysis," then Factor XIII, 1:1 Mix (Sendout) [RF13MX] will be performed at additional charge.
- Synonyms
- 3016927, Clot Solubility, F13, Factor 13, Factor XIII, Fibrin Stabilizing Factor, FX13M, FXIII, Urea Solubility
Interpretation
- Method
Qualitative Solubility Assay
- Reference Range
-
Female Male Age Range Age Range 0- No Lysis [NOLYS] 0- No Lysis [NOLYS] Effective date: 02/01/2024
- Ref. Range Notes
Reference Range:
Factor XIII, Qualitative: No Lysis within 24 hours - Interferences and Limitations
Cautions: False-positive results (lysis) can be caused by heparin (therapy with unfractionated or low molecular weight heparin or contamination from a line), decreased or abnormal fibrinogen, increased fibrinolysis (inherited or acquired fibrinolytic disorders), fibrinolytic drugs, or other factors that affect clot structure or stability.
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
5 mL BLUE TOP (sodium citrate) tube
- Handling Instructions
Outside Laboratories:
- Centrifuge for 10 minutes and remove plasma.
- Centrifuge the plasma again for another 10 minutes.
- Transfer 2 mL platelet-poor plasma into a separate plastic aliquot (minimum 1 mL). Freeze plasma at -20°C.
Stability: Frozen (required): 2 weeks; Ambient: 4 hours; Refrigerated: Unacceptable.
- Note: Critical Frozen. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions: Serum, EDTA plasma, clotted or hemolyzed specimens.
- Quantity
-
requested: 2 mL platelet-poor plasma
minimum: 1 mL platelet-poor plasma
Processing
- Processing
UW-MT: Immediately forward specimens to Coagulation Lab for processing. Coag: Double-spin the sample and aliquot 2 mL platelet-poor plasma into a separate plastic aliquot (minimum 1 mL). Freeze plasma at -20°C (place in the UW Sendouts frozen rack).
HMC: Immediately forward specimens to Coagulation Lab for processing. Coag: Double-spin the sample and aliquot 2 mL platelet-poor plasma into a separate plastic aliquot (minimum 1 mL). Freeze plasma at -20°C. Forward to UW-MT for sendout.
UW-NW or Fred Hutch: Centrifuge for 10 minutes and remove plasma. Centrifuge the plasma again for another 10 minutes. Transfer 2 mL platelet-poor plasma into a separate plastic aliquot (minimum 1 mL). Freeze plasma at -20°C. Forward to UW-MT for sendout.
Sendouts:
- Order ARUP Test: 3016927.
- Interfaced: Yes. [Interface: 602; Department: ARPZ]
Stability: Frozen (required): 2 weeks; Ambient: 4 hours; Refrigerated: Unacceptable.
- Note: Critical Frozen. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions: Serum, EDTA plasma, clotted or hemolyzed specimens.
Performance
- LIS Dept Code
- Sendouts ARUP Lab (FZ) (ARPZ)
- Performing Location(s)
-
Sendout ARUP Laboratories, Inc.
800-522-2787500 Chipeta Way
Salt Lake City, UT 84108 - Frequency
- Performed: Sunday through Saturday. Reported: 2-3 days from sample receipt at ARUP.
- Available STAT?
- No
Billing & Coding
- CPT codes
- 85291
- LOINC
- 3241-7
- Interfaced Order Code
- UOW3963
- Interfaced Result Code
- UOW3963