Desmoglein 1 and 3 IgG Antibodies (Sendout)

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General Information

Lab Name
Desmoglein 1 and 3 IgG Antibodies (Sendout)
Lab Code
RDES13
Epic Ordering
Desmoglein 1 and 3 IgG Antibodies (Sendout)
External Test Id
0090649
Description

Ordering Recommendation: Use to monitor disease in patients diagnosed with various pemphigus variants and increased IgG desmoglein 1 and/or IgG desmoglein 3 antibodies; antibody levels correlate with disease activity.

References
Forms & Requisitions
Synonyms
0090649, Anti-Desmoglein 1, Anti-Desmoglein 3, Desmoglein 1, Desmoglein 3, desmosomal protein antibodies, desmosome antibodies, DSG1, DSG3, DSGAB, endemic pemphigus, fogo selvagem, ICS antibodies, Pemphigus erythematosus, Pemphigus foliaceus, Pemphigus vegetans, Pemphigus vulgaris, RDS13G
Components

Interpretation

Method

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reference Range
See individual components
Ref. Range Notes

Desmoglein 1 IgG Antibody:

Normal (Negative): <14 U/mL
Borderline/Indeterminate: 14-20 U/mL
Increased (positive): >20 U/mL

Desmoglein 3 IgG Antibody:

Normal (Negative): <9 U/mL
Borderline/Indeterminate: 9-20 U/mL
Increased (positive): >20 U/mL
References

Ordering & Collection

Specimen Type
Blood
Collection

6 mL in RED TOP tube or GOLD SST

Forms & Requisitions
Handling Instructions

Outside Laboratories:

Stability: Refrigerated (preferred): 2 weeks; Frozen: Indefinitely; Ambient: 1 week.

Unacceptable Conditions: Hemolyzed or lipemic specimens, plasma.

Quantity
requested: 2 mL serum
minimum: 0.5 mL serum

Processing

Processing

Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Sendouts:

  • Order ARUP Test: 0090649
  • Interfaced: No
  • If the (optional) Immunodermatology Form was completed, include it with the ARUP batch sheet.

Stability: Refrigerated (preferred): 2 weeks; Frozen: Indefinitely; Ambient: 1 week.

Unacceptable Conditions: Hemolyzed or lipemic specimens, plasma.

Performance

LIS Dept Code
Sendouts (SO)
Performing Location(s)
Sendout ARUP forwards to University of Utah Immunodermatology Laboratory
800-242-2787

417 S. Wakara Way
Suite 2151
Salt Lake City, UT 84108

Immunodermatology Lab (Direct): 801-581-7139

Frequency
Performed: Varies. Reported: 3-9 days from sample receipt at ARUP Laboratories.
Available STAT?
No

Billing & Coding

CPT codes
83516x2
LOINC
94335-7
Interfaced Order Code
UOW4786