Chikungunya Virus IgG and IgM Antibodies (Sendout)

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General Information

Lab Name
Chikungunya Virus IgG and IgM Antibodies (Sendout)
Lab Code
RCHIKV
Epic Ordering
Chikungunya Virus IgG and IgM Antibodies (Sendout)
External Test Id
2011812
Description

Ordering Recommendation: May aid in the diagnosis of chikungunya viral infection during acute phase of disease (>5 days after symptom onset). Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

Collection Note: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Specimens must be plainly marked as "acute" or "convalescent."

References
Synonyms
2011812, Arbovirus, CHIKPAN, Chikungunya, CHIKV
Components

Interpretation

Method

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reference Range
See individual components
Ref. Range Notes

Chikungunya Antibody, IgG:

Index: Interpretation:
0.79 IV or less Negative: No significant level of Chikungunya IgG antibody detected.
0.80-1.09 IV Equivocal: Questionable presence of Chikungunya IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater Positive: Chikungunya IgG antibody detected; suggests current or past infection.

Chikungunya Antibody, IgM:

Index: Interpretation:
0.79 IV or less Negative: No significant level of Chikungunya IgM antibody detected.
0.80-1.09 IV Equivocal: Questionable presence of Chikungunya IgM antibody detected. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater Positive: Chikungunya IgM antibody detected.
References
Guidelines

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in GOLD SST or RED TOP tube

Also Accepted: Green top (Heparin) or Lavender top (EDTA) tube

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum/plasma to a separate plastic vial within 2 hours of collection. Refrigerate serum/plasma.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hours. Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Quantity
requested: 1 mL serum or plasma
minimum: 0.15 mL serum or plasma

Processing

Processing

Centrifuge sample and transfer serum/plasma to a separate plastic vial within 2 hours of collection. Refrigerate serum/plasma.

Sendouts:

  • Order ARUP Test: 2011812
  • Interfaced: Yes [Interface: 602; Department: ARPR]
  • If parallel testing will be performed:
    • Mark serum samples as "acute" or "convalescent," as appropriate. Convalescent samples must be received by ARUP within 30 days from receipt of the acute sample.
    • On the Sunquest-generated batch sheet, indicate "run parallel testing with acute sample collected (MM/DD/YY)" next to the associated order.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hours. Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Performance

LIS Dept Code
Sendouts ARUP Lab (RF) (ARPR)
Performing Location(s)
Sendout ARUP Laboratories, Inc.
800-522-2787

500 Chipeta Way
Salt Lake City, UT 84108

Frequency
Setup Wednesday. Results in 1-8 days.
Available STAT?
No

Billing & Coding

CPT codes
86790x2
LOINC
43064-5