Maternal Cell Contamination Comparator

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General Information

Lab Name
Maternal Cell Contamination Comparator
Lab Code
MCCOMP
Epic Ordering
Maternal Cell Contamination Comparator
Description

This test is for the comparator sample used to evaluate fetal tissue for contamination by maternal cells. It usually consists of a tube of whole blood from the mother; saliva and extracted DNA are also accepted.

Both this test and Maternal Cell Contamination, Fetal [MCC] must be ordered in order for the laboratory to perform maternal cell contamination studies.

See Maternal Cell Contamination, Fetal [MCC] for more information.

Synonyms
amniocyte contamination, control, DNA fingerprinting, fetal testing, Maternal Cell Contamination, MCC studies, prenatal testing

Interpretation

Reference Range

Ordering & Collection

Specimen Type
Blood, extracted DNA, or saliva
Collection

Whole blood:
5 mL LAVENDER TOP tube.
Also acceptable: YELLOW TOP (ACD) tube.

Unacceptable: Heparin green top tubes.

Extracted DNA:
1 ug (concentration >10 ng/uL).

Saliva:
Contact laboratory for validated collection kit.

Forms & Requisitions

Due to the complexity of prenatal testing, consultation with the laboratory is required.

Please contact the Genetics lab by e-mail (genelab@uw.edu) or phone (206-598-1149).

Outside providers: Genetics Requisition.

UW, HMC, and FHCC providers: Place order in Epic.

Handling Instructions

Whole blood: Refrigerate up to 1 week.

Extracted DNA: Frozen is preferred. Refrigerated is acceptable.

Saliva: Contact laboratory for a validated collection kit. Keep at room temperature.

Outside Laboratories
Whole blood: Ship at ambient temperature for receipt within 1 week of specimen collection.

Extracted DNA: Ship on a cold pack.

Saliva: Contact laboratory for a validated collection kit. Ship at room temperature.

Quantity
requested: Entire specimen.
minimum: Blood: 1 mL. Extracted DNA: 500 ng. Saliva: Per kit instructions.

Processing

Processing

Performance

LIS Dept Code
Genetics (GEN)
Performing Location(s)
UW-MT Genetics

Attention: Genetics Lab
Clinical lab, Room NW220
University of Washington Medical Center
1959 NE Pacific Street
Seattle, WA 98195

Tel: 206-598–6429 M–F (7:30 AM–4:00 PM)
Fax: 206-616-4584
Lab email: cgateam@uw.edu

Tel (EXOME only): 206-543-0459

Faculty
Jillian Buchan, PhD, FACMG
Runjun Kumar, MD, PhD
Regina Kwon, MD, MPH
Christina Lockwood, PhD, DABCC, DABMGG
Abbye McEwen, MD, PhD
Colin Pritchard, MD, PhD
Vera Paulson, MD, PhD
Eric Konnick, MD, MS
He Fang, PhD

Frequency
MCC studies are performed weekly once both the primary sample and comparator are received. Results within 2 weeks.
Available STAT?
No

Billing & Coding

CPT codes
LOINC
26436-6
Interfaced Order Code
UOW4222
Interfaced Result Code
UOW4222