HIV1 RNA Quantitation

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General Information

Lab Name
HIV1 RNA Quantitation
Lab Code
HRTABB
Epic Ordering
HIV1 Rna Quantitation
Description

The UW Clinical Virology Laboratory in the Department of Laboratory Medicine and Pathology incorporates the FDA approved Roche cobas® HIV-1 quantitative assay for the detection and quantitation of human immunodeficiency virus type 1 in EDTA plasma using real-time PCR amplification.

The range of quantitation of HIV-1 RNA is 20 to 10,000,000 copies/mL (33 to 1.67 x 107 International Units/mL).

The Roche cobas® HIV-1 quantitative assay uses primers specific for the HIV-1 gag gene and the HIV-1 LTR region (dual target).

Synonyms
HIV PCR, HIV Viral Load
Components

Interpretation

Method

Real-time Polymerase Chain Reaction

Reference Range
See individual components
Guidelines

Ordering & Collection

Specimen Type
Plasma (EDTA)
Collection

Blood: EDTA plasma or PPT

Unacceptable: plasma from GREEN TOP (Heparin), YELLOW (ACD) or GRAY (Oxylate) and serum (No RED TOP)

Handling Instructions

Freshly drawn whole blood may be stored and/or transported for up to 24 hours at 2°C to 25°C prior to plasma preparation through centrifugation.

Quantity
requested: 2.0 mL plasma
minimum: 0.75 mL plasma

Processing

Processing

Blood: Centrifugation upon arrival, remove plasma from cells.

Plasma may be stored and/or transported:

2°C to 8°C for up to 6 days
-18°C ± 2°C for up to 12 weeks
-75°C ± 15°C for long term storage up to 6 months. Avoid multiple freeze/thaw cycles.


Outside Laboratory: Plasma may be stored at 2°C to 8°C for up to 6 days after collection. To ensure testing is completed within this 6-day window, shipment time should not exceed 48 hours from the time of collection, and samples should be shipped on wet ice (ice pack). Alternatively, samples can be frozen at -18°C or colder and shipped on dry ice for extended preservation.

Performance

LIS Dept Code
Central Lab Virology (RVIR)
Performing Location(s)
CL Virology, Renton
206-685-6656

1602 Raymond Ave SW

Renton, WA 98057-3356

206-685-6656 opt 4

Frequency
Tuesday - Saturday. Results same day.
Available STAT?
No

Billing & Coding

CPT codes
87536
LOINC
49890-7
Interfaced Order Code
UOW1094