Heme Amplicon Panel by NGS

General Information

Lab Name

Heme Amplicon Panel by NGS

Lab Code

HOTSPT

Epic Name

Heme Amplicon Panel by NGS

Description

UW Heme Amplicon panel is a multiplexed gene panel assay that detects mutations related to treatment, prognosis, or diagnosis in the setting of hematolgical malignancy. The regions of the genes included in the panel are amplified using amplification technology and sequenced on an Illumina instrument to detect single nucleotide variants, insertions, and deletions. This test is designed to detect somatic mutations in the setting of neoplasia, and is not designed to detect germline (heritable) mutations.

Synonyms

11-17, 14, 15, 16), 17), 26, 27), 3, 6), 6), amplicon panel, ASXL1 (CDS), CBL (CDS), CSF3R (Exons 14, DNMT3A (CDS), EZH2 (Exons 15-20), FBXW7 (CDS), FGFR1 (Exons 4, FLT3 (p.D835H), GATA1 (Exons 2-3), GATA2 (Exons 3-5), Hotspot, HRAS (Exon 1-2), IDH1( p.R132), IDH2 (Exon 4), JAK2 (Exon 12, KIT (8-18), KMT2A (CDS), KRAS (CDS), MAP2K1 (Exons 2, MPL (Exon 10), multigene panel, MYD88 (Exon 3-5), next-generation sequencing, NGS, NOTCH1 (Exons 20, NPM1 (Exon 12), NRAS (CDS), partial 18), PDGFRA (Exons 12-18), PHF6 (CDS), PTEN (CDS), RB1 (CDS), RUNX1 (Exon 4-8), SF3B1 (Exon 14-16), SRSF2 (Exon 1), STAG2 (CDS), STAT3 (Exons 20-21), TET2 (CDS), TP53 (CDS), U2AF1 (Exons 2, WT1 (CDS), ZRSR2 (CDS)

Components

Code	Name
HOTSD	Heme Gene Panel Spec. Desc.
HOTRES	Heme Gene Panel Result
HOTINT	Heme Gene Panel Interpretation
HOTG	Heme Panel Genes Analyzed
HOTM	Heme Gene Panel Method