Factor II Activity
General Information
- Lab Name
- Factor II Activity
- Lab Code
- F2
- Epic Name
- Factor II Activity
- Description
This test is NOT for Factor II Mutation, Factor II DNA or Prothrombin DNA. For Factor II Mutation or Factor II DNA, see: PRODS
Factor II (2) activity is used for diagnosing rare congenital factor II deficiency, investigation of prolonged prothrombin time and evaluating acquired deficiency associated with liver disease or vitamin K dependent factor deficiency. Occasionally, prolonged Prothrombin Time and decreased Factor 2 activity can be seen in patients with lupus anticoagulants or antiphospholipid antibodies with specificity for prothrombin (factor II).
- Synonyms
- Factor 2
- Components
Interpretation
- Method
Stago STA Clottable Factor assay
- Reference Range
-
Units: %
Female Male Age Range Age Range 0-29d 33-150 0-29d 33-150 1m-2m 34-150 1m-2m 34-150 3m-5m 45-150 3m-5m 45-150 6m- 50-150 6m- 50-150 Effective date: 08/14/2024
- Interferences and Limitations
Patients on bivalirudin (Angiomax), dabigatran (Pradaxa), argatroban (Novastan), rivaroxaban (Xarelto), apixaban (Eliquis), and edoxaban (Savaysa) may show prolonged clotting times. This may cause an under- estimation of the factor concentrations.
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
3 or 5 mL BLUE TOP (CITRATE) tube
- Forms & Requisitions
Outside clients should fill and submit Coagulation Patient Clinical History Form: Coagulation Patient Clinical History Form
- Handling Instructions
The Laboratory MUST process specimen, within 4 hrs of blood collection.
- Quantity
- Requested: entire specimen
Processing
- Receiving Instructions
UW-MT Instructions: Take specimen to UW-MT Coag lab for processing. Coag Tech will freeze plasma sample for transport to HMC Coag.
HMC Instructions: Take specimen to HMC Coag lab for processing.
Outside Laboratory: Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) @ -20°C to -80°C. Send frozen on dry ice.
- Misc Sendout
Performance
- Lab Department
- Coagulation(COAG)
- Frequency
- Run Monday-Friday. Reported by end of day.
- Available STAT?
- No
- Performing Location(s)
-
HMC Coagulation
206-520-4600325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420
Billing & Coding
- CPT Codes
- 85210
- LOINC
- 3289-6
- Interfaced Order Code
- UOW1281
- Interfaced Result Code
- UOW1281