BROCA add-on to ColoSeq

General Information

Lab Name

BROCA add on to ColoSeq

Lab Code

COSQBA

Epic Ordering

BROCA ADD ON TO COLOSEQ

Description

BROCA add-on to ColoSeq(TM) is intended for patients who have tested negative for mutations ColoSeq(TM) Lynch and Polyposis panel who would benefit from full BROCA panel. The panel tests for additional genes that confer hereditary cancer risk. BROCA add-on to ColoSeq (TM) uses next-generation sequencing to detect most mutations in ATM, ATR, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDK4, CDKN2A, CHEK1, CHEK2, FAM175A (Abraxas), GALNT12, GEN1, MRE11A, NBN, PALB2, PRSS1, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RET, TP53BP1, UIMC1, VHL, and XRCC2. The assay completely sequences all exons of these genes AND detects large deletions and duplications. For additional information or to order this test, see: BROCA add on to ColoSeq billing information

Genetics Requisition

BROCA Cancer Risk Panel [BROCA]

Forms & Requisitions

Genetics Requisition

Synonyms

ATM, BARD1, BRCA1, BRCA2, BRCA-negative reflex test, Breast Cancer, BRIP1, CHEK2, ColoSeq™-negative reflex test, DNA, Hereditary Cancer panel, MRE11A, multi-gene panel, NBN, Next-generation sequencing, Ovarian Cancer, PALB2, PTEN, RAD51B, RAD51D

Components

Code	Name
CTOBRE	BROCA add to ColoSeq Result
CTOBIN	BROCA add to ColoSeq Interpret
CTOBCH	BROCA add to ColoSeq Clin Hx
CTOBMT	BROCA add to ColoSeq Method

Interpretation

Method: Next-generation sequencing
Reference Range: See individual components
Ref. Range Notes: No mutations detected

Ordering & Collection

Specimen Type: Peripheral Blood
Collection: 10 mL whole blood in LAVENDER TOP EDTA tube.
Also acceptable: ACD
Forms & Requisitions: Genetics Requisition
Handling Instructions: Ship at room temperature overnight delivery. OK to hold up to 7 days before shipping if refrigerated.
Quantity: requested: entire sample
minimum: 5 mL whole blood

Processing

Processing

Performance

LIS Dept Code

Genetics (GEN)

Performing Location(s)

UW-MT	Genetics Attention: Genetics Lab Clinical lab, Room NW220 University of Washington Medical Center 1959 NE Pacific Street Seattle, WA 98195 Tel: 206-598–6429 M–F (7:30 AM–4:00 PM) Fax: 206-598–0304 Lab email: cgateam@uw.edu Tel (EXOME only): 206-543-0459	Manager Joe Bernal Genetic Counselors Angela Jacobson, MS, LGC Sandra Coe, MS,LGC Dru Leistritz, MS, LGC(EXOME testing only) Variant Review Scientist Ankita Jhuraney, PhD Sarah Paolucci, MA, MS, LGC Catherine A. Darcey, MSc Daniel W. Serber, PhD, MS, LCGC Faculty Jillian Buchan, PhD, FACMG Runjun Kumar, MD, PhD Christina Lockwood, PhD, DABCC, DABMGG Brian Shirts, MD, PhD Abbye McEwen, MD, PhD Colin Pritchard, MD, PhD Vera Paulson, MD, PhD Eric Konnick, MD, MS He Fang, PhD

Frequency

Results in 5-6 weeks.

Available STAT?

Billing & Coding

CPT codes
Billing Comments: For additional test/billing information, see following page: BROCA add-on to ColoSeq billing information.
LOINC: 26435-8
Interfaced Order Code: UOW2689