ANA Differentiator Panel

General Information

Lab Name

Lab Code

ANADP

Epic Name

ANA Differentiator Panel

Description

Initial screen includes ANA screen by IFA and by multiplex (ANARC). The multiplex screen detects the following antibodies: anti chromatin, ribosomal P, Sm, Sm/RNP, RNP, SSA/Ro, SSB/La, Centromere B, Scl70, and Jo1.

If either screening test is positive, identification panel ANARC2 will be performed at an additional charge.

If the multiplex screen is not positive and the ANA by IFA has a pattern consistent with anti-DFS70, ANARC4 will be added at a additional charge.

Synonyms

ADFS70, ANA Cascade, ANA Comprehensive Plus Panel, ANARC

Components

Code	Name
ANADP1	ANA Panel
ANACP	ANA Panel Order
ANADFO	Anti DFS70 Reflex
ANARC	ANA Reflex Comprehensive Panel
ANASC	Antibodies to Nuclear Antigens by Immunofluorescence
ANAPA	ANA Pattern by IF
ANAPA1	ANA Immunofluorescence Pattern
ANAPA2	ANA Immunofluorescence Pattern 2
ANAPA3	ANA Immunofluorescence Pattern 3
ANACYT	Hep2 Cytoplasmic Pattern
ANABIO	ANA Screen by Multiplex
ANAI1	ANA Interpretation Comment 1

Interpretation

Guidelines

Specialty Testing in Immunology

Method

IFA and multiplex immunoassay

Reference Range

See individual components

Interferences and Limitations

Grossly hemolyzed or lipemic serum may produce increased nonspecific background staining of substrate.

Ordering & Collection

Specimen Type: Blood
Collection: 6 mL blood in a RED TOP or GOLD SST tube
Handling Instructions: Centrifuge and separate serum within 2 hours of collection. Refrigerate serum (only one aliquot needed).

Stability: Room Temperature: up to 8 hours; Refrigerated: 14 days; Frozen at -20°C or colder: Long Term
Quantity: Requested: 2 mL serum
Minimum: 1.5 mL serum

Processing

Receiving Instructions: Centrifuge and separate serum within 2 hours of collection. Refrigerate serum (only one aliquot needed).

Stability: Room Temperature: up to 8 hours; Refrigerated: 14 days; Frozen at -20°C or colder: Long Term

Misc Sendout

Performance

Lab Department

Frequency

Monday-Friday, Negative ANA by IFA results same day. Positive results, reflex tests within 2 weeks.

Available STAT?

Performing Location(s)

CL	Immunology Lab 206-520-4600 Room# 573 1601 Lind Ave SW Renton, WA 98057	Hours of Operation: Monday–Friday, 8:00 AM–5:00 PM PST Phone: (206) 485-9268

Billing & Coding

CPT Codes: 86038
LOINC: 18727-8
Interfaced Order Code: UOW3234