Rocky Mountain Spotted Fever Antibodies, IgG and IgM (Sendout)

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General Information

Lab Name
Lab Code
453
External Test Id
0050371
Description

Ordering Recommendation: Rocky Mountain spotted fever (RMSF) is a severe tick-borne infection caused by the bacterium Rickettsia rickettsii. Preferred test for acute or convalescent phase of disease. Acute and convalescent titers often necessary.

References
Synonyms
0050371, Rickettsia Rickettsii, RMSF, Rocky Mountain Spotted Fever

Interpretation

Method

Semi-Quantitative Indirect Fluorescent Antibody

Ref. Range Notes

Reference Ranges:

Rocky Mt Spotted Fever IgG: <1:64
Rocky Mt Spotted Fever IgM: <1:64

Interpretation:

Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibody, IgG:

Less than 1:64: Negative - No significant level of IgG antibody detected.
1:64 - 1:128: Low Positive - Presence of IgG antibody detected, suggestive of current or past infection.
1:256 or greater: Positive - Presence of IgG antibody suggestive of recent or current infection.

Rickettsia rickettsii (Rocky Mountain Spotted Fever) Antibody, IgM:

Less than 1:64: Negative - No significant level of IgG antibody detected.
1:256 or greater: Presence of IgM antibody detected, which may indicate a current or recent infection; however, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
References
Guidelines

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in RED TOP tube or GOLD SST

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Samples must be clearly marked as "acute" or "convalescent."

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeat freeze/thaw cycles); Ambient: 48 hours.

Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.

Quantity
requested: 1 mL serum
minimum: 0.5 mL serum

Processing

Processing

Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Sendouts:

  • Order ARUP Test: 0050371
  • Interfaced: Yes [Interface: 602; Department: ARPR]
  • Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Samples must be clearly marked as "acute" or "convalescent."

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeat freeze/thaw cycles); Ambient: 48 hours.

Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.

Performance

LIS Dept Code
Performing Location(s)
Sendout ARUP Laboratories, Inc.
800-522-2787

500 Chipeta Way
Salt Lake City, UT 84108
Frequency
Performed: Sunday - Saturday. Reported: 1-3 days.
Available STAT?
No

Billing & Coding

CPT codes
Billing Comments

CPTs: 86757 x2

LOINC