Rickettsia typhi Antibodies, IgG and IgM (Sendout)

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General Information

Lab Name
Lab Code
372
External Test Id
0050384
Description

Ordering Recommendation: Confirm presence of Rickettsia typhi. Requires comparison of acute- to convalescent-phase serology. Flea-borne (murine) typhus, is a disease caused by a bacteria called Rickettsia typhi.

References
Synonyms
0050384, Murine Typhus Antibodies, R. typhi antibodies, Typhus Fever

Interpretation

Method

Semi-Quantitative Indirect Fluorescent Antibody

Ref. Range Notes

Reference Ranges:

Typhus Fever Antibody, IgG <1:64
Typhus Fever Antibody, IgM <1:64

Interpretation:

Rickettsia typhi (Typhus Fever) Antibody, IgG by IFA:

Less than 1:64: Negative - No significant level of IgG antibody detected.
1:64-1:128: Equivocal - Questionable presence of IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1:256 or greater: Positive - Presence of IgG antibody detected, suggestive of current or past infection

Rickettsia typhi (Typhus Fever) Antibody, IgM by IFA:

Less than 1:64: Negative - No significant level of IgM antibody detected.
1:64 or greater: Positive - Presence of IgM antibody to detected, which may indicate a current or recent infection; however, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
References
Guidelines

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in RED TOP tube or GOLD SST

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Samples must be clearly marked as "acute" or "convalescent."

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeat freeze/thaw cycles); Ambient: 48 hours.

Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.

Quantity
requested: 1 mL serum
minimum: 0.5 mL serum

Processing

Processing

Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Sendouts:

  • Order ARUP Test: 0050384
  • Interfaced: Yes [Interface: 602; Department: ARPR]
  • Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Samples must be clearly marked as "acute" or "convalescent."

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year (avoid repeat freeze/thaw cycles); Ambient: 48 hours.

Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.

Performance

LIS Dept Code
Performing Location(s)
Sendout ARUP Laboratories, Inc.
800-522-2787

500 Chipeta Way
Salt Lake City, UT 84108
Frequency
Performed: Sunday - Saturday. Reported: 1-3 days.
Available STAT?
No

Billing & Coding

CPT codes
Billing Comments

CPTs: 86757x2

LOINC