Hepatitis B Virus Genotype by Sequencing (Sendout)

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General Information

Lab Name
Lab Code
1026
External Test Id
2001567
Description

Ordering Recommendation: Determine antiviral drug resistance by DNA sequencing.

Synonyms
2001567, Adefovir, Entecavir, HBsAg mutations, HBV drug resistance testing, HBV Genotype, HBV Genotyping, HBV Resistance, HBV Resistance Sequencing, HBV Sequencing, Hepatitis B Drug Resistance Panel, Lamivudine, Telbivudine, Tenofovir

Interpretation

Method

Polymerase Chain Reaction/Sequencing

Ref. Range Notes

Reference Interval: See report.

Interpretive Data: Both the HBV RT polymerase and the HBsAg encoding regions are sequenced. Resistance and surface antigen mutations are reported. In addition, the major HBV genotypes are identified. Mutations in viral sub-populations below 20 percent of total may not be detected.

Interferences and Limitations

This test may be unsuccessful if the HBV viral load is less than log 3.0 or 1,000 IU/mL of plasma.

Guidelines

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in LAVENDER TOP (EDTA)

  • Also Accepted: GOLD SST or Pearl Top PPT
Handling Instructions

Outside Laboratories: Centrifuge sample and transfer plasma or serum to a separate plastic vial. Freeze plasma/serum at -20 °C while awaiting shipment. Transport on dry ice.

Stability: Frozen: 6 weeks; Refrigerated: 1 week; Ambient: 72 hours.

Quantity
requested: 2 mL plasma or serum
minimum: 0.5 mL plasma or serum

Processing

Processing

Centrifuge sample and transfer plasma or serum to a separate plastic vial. Freeze plasma/serum at -20°C.

Sendouts:

  • Order ARUP Test: 2001567
  • Interfaced: Yes [Interface: 602; Department: ARPZ]

Stability: Frozen: 6 weeks; Refrigerated: 1 week; Ambient: 72 hours.

Performance

LIS Dept Code
Performing Location(s)
Sendout ARUP Laboratories, Inc.
800-522-2787

500 Chipeta Way
Salt Lake City, UT 84108
Frequency
Performed: Tuesday, Friday. Reported: Within 10 days from sample receipt at ARUP Laboratories.
Available STAT?
No

Billing & Coding

CPT codes
Billing Comments

CPT: 87912

LOINC